if statement with multiple operators and conditions from PHP

I want an en to be executed, PHPbut only if any of the 4 buttons are clicked . The problem is that when the page loads, the instruction inside the with is still executed , but I only need it (as I said before) to only be executed when some of those buttons are clicked and nothing else.insertmysqliifinsert

Maybe I'm putting the if, the parentheses wrong, or the use and location of the operators. I have already tried some other combinations and it continues to enter insertwithout even having clicked on the buttons. As you can see I put all the conditions in the same if, maybe I should separate it into different ones if. I hope you can tell me what would be more effective and that works of course. The code of PHPis:

if(isset($_POST['Ant']) && !empty($_POST['Ant']) || 
  (isset($_POST['Sig']) && !empty($_POST['Sig'])) || 
  (isset($_POST['Pri']) && !empty($_POST['Pri'])) || 
  (isset($_POST['Ult']) && !empty($_POST['Ult'])))
    {
      $sql=mysqli_prepare($cxn,"Insert into esttips (ID,NroTips,UserIP,Fecha) 
      Values (?,?,?,?)");
      mysqli_stmt_bind_param($sql,'siss',$id,$F,$ip,$fecha2);
      if (!mysqli_stmt_execute($sql)) {die('Error: ' . mysqli_error($cxn));}
    }

I will explain a little better. I must clarify that I have all the code in the same file ( index.php ). The button clicks event is done in JQuerymaking use of AJAXwhich is already working:

$('body').on('click', '#Ant, #Sig, #Pri, #Ult', function(e) {
 ...
 ...
}

I only need, as I mentioned at the beginning, that when any of the buttons is clicked ( #Ant, #Sig, #Pri, #Ult) it makes the insertion in the MySQL database that I have. But it can be seen that since all the code is in the same file, when loading the page it already inserts the values, when I only want it to do so only when a button is clicked.

Can everything be done in the same index.php or should I do the php thing separately in another file and then from the index.php make the call?